Volume 29, Issue 178 (11-2019)
J Mazandaran Univ Med Sci 2019, 29(178): 34-41 |
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Mahmoodi Nesheli H, Barari Sawadkohi R, Khafri S, Jokaar F, Jamshidvand O, Tamaddoni A. Prevalence of HCVAb and HBsAg in Patients with Beta-thalassemia Major in Amirkola Thalassemia Center. J Mazandaran Univ Med Sci 2019; 29 (178) :34-41
URL: http://jmums.mazums.ac.ir/article-1-13938-en.html
URL: http://jmums.mazums.ac.ir/article-1-13938-en.html
Prevalence of HCVAb and HBsAg in Patients with Beta-thalassemia Major in Amirkola Thalassemia Center
Hassan Mahmoodi Nesheli 
, Rahim Barari Sawadkohi , Soraya Khafri , Fazilat Jokaar , Omidreza Jamshidvand , Ahmad Tamaddoni
, Rahim Barari Sawadkohi , Soraya Khafri , Fazilat Jokaar , Omidreza Jamshidvand , Ahmad Tamaddoni
Abstract: (7146 Views)
Background and purpose: Beta-thalassemia major is a genetic disorder with known globin defect that leads to chronic hemolytic anemia. Due to the need for recurrent blood transfusion, the risk of infectious diseases such as hepatitis is higher in these patients.
Materials and methods: This cross-sectional study recruited 518 patients with thalassemia major in Amirkola Thalassemia Center, 2013-2014 who were selected via census sampling. Patients' blood samples were analyzed for HBsAb, HBsAg, and HCVAb by ELISA test. Data were analyzed in
SPSS V22.
Results: The patients included 268 (51.7%) females and 250 (48.3%) males with the mean age of 27.93±9.88 years. The study showed that 5.79% of patients with thalassemia major were infected with HCV, including 11 (4.4%) males and 19 (7.1%) females and only one male patient was found to be HBsAg positive.
Conclusion: The study showed lower incidence of hepatitis C compared to previous reports from Amirkola Thalassemia Center. In current study the prevalence of HBsAg was also found to be low.
Materials and methods: This cross-sectional study recruited 518 patients with thalassemia major in Amirkola Thalassemia Center, 2013-2014 who were selected via census sampling. Patients' blood samples were analyzed for HBsAb, HBsAg, and HCVAb by ELISA test. Data were analyzed in
SPSS V22.
Results: The patients included 268 (51.7%) females and 250 (48.3%) males with the mean age of 27.93±9.88 years. The study showed that 5.79% of patients with thalassemia major were infected with HCV, including 11 (4.4%) males and 19 (7.1%) females and only one male patient was found to be HBsAg positive.
Conclusion: The study showed lower incidence of hepatitis C compared to previous reports from Amirkola Thalassemia Center. In current study the prevalence of HBsAg was also found to be low.
Type of Study: Research(Original) |
Subject:
Pediatric Hematology and Oncology
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