Volume 30, Issue 193 (1-2021)                   J Mazandaran Univ Med Sci 2021, 30(193): 21-37 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Shirvanirad S, Nikkhah A, Orvatinia M M, Ejtahed H, Sarhangi N, Aghaei Meybodi H R et al . The Microbiome in Precision Medicine: A New Approach to Cancer Treatment. J Mazandaran Univ Med Sci 2021; 30 (193) :21-37
URL: http://jmums.mazums.ac.ir/article-1-16110-en.html
Abstract:   (2672 Views)
Precision medicine is a new approach in medical sciences aimed at individualizing treatment, reducing adverse drug reactions (ADRs), and decreasing health care costs. Precision medicine is also able to maintain the health of individuals by regulating their composition of microorganisms (microbiota) using specific methods. Microbiota is the total stock of microbial species in different organs of a human body and their set of genes are called microbiome. The composition of microbiota is unique in each individual and is directly associated with genetic and invironmental facors, including lifestyle, and certain medications. The human gut is strongly influenced by bacterial communities. Evidence suggests that gut microbiota is involved in oncological diseases. Therefore, microbiota plays a key role in maintaining human health and reducing the risk of diseases in unstable environments. Generally, the microbiome appears to be a vital part of the precision medicine approach, since it leads to interpersonal diversity in all facets of a disease and also represents a changeable component that could increasingly be considered as a therapeutic target and improve drug resistance and responses. In this review, we highlight the importance of the gut microbiota and microbiome in cancer and their functions as therapeutic biomarkers in precision medicine approach.
Full-Text [PDF 616 kb]   (1054 Downloads)    
Type of Study: Review | Subject: Microbiota Special Issue

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb