Volume 35, Issue 251 (12-2025)
J Mazandaran Univ Med Sci 2025, 35(251): 253-264 |
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mahjoub F, Azad Manjiri M, Ghazanfari S M, Farahmand S K, Salari R. A Comprehensive Review of the Therapeutic Applications of Cynodon dactylon in Persian Medicine and Contemporary Scientific Research. J Mazandaran Univ Med Sci 2025; 35 (251) :253-264
URL: http://jmums.mazums.ac.ir/article-1-22353-en.html
URL: http://jmums.mazums.ac.ir/article-1-22353-en.html
Fatemeh Mahjoub 
, Mohammad Azad Manjiri , Seyed Majid Ghazanfari , Seyed Kazem Farahmand , Roshanak Salari
, Mohammad Azad Manjiri , Seyed Majid Ghazanfari , Seyed Kazem Farahmand , Roshanak Salari
Abstract: (21 Views)
Thill (Cynodon dactylon) is regarded as one of the most important medicinal plants in Persian medicine, historically used to treat a wide range of ailments due to the therapeutic value of its various parts. Recent research has further highlighted its broad pharmacological activities. This review article was developed to integrate historical and contemporary insights on Thill, with the aim of clarifying its role from ancient medical traditions to modern scientific investigations and identifying promising avenues for future research. To achieve this, the traditional uses, phytochemical constituents, and pharmacological properties of the plant were examined using sources ranging from classical Persian medical texts to recent scientific studies. The data for this review were collected from authoritative Persian sources dating back several centuries, including al-Ḥāwī, The Canon of Medicine, and al-Ṣaydanah fi al-Tibb, alongside additional traditional references. Electronic databases such as Web of Science, ScienceDirect, PubMed, EMBASE, Scopus, EBSCO, Google Scholar, SID, and IranMedex were also systematically searched. The findings show that Persian medical literature attributes numerous digestive and urogenital benefits to this plant. Phytochemical analyses confirm that Cynodon dactylon contains a wide spectrum of bioactive compounds, including carbohydrates, proteins, flavonoids, alkaloids, phenolic compounds, terpenoids, carotenoids, saponins, glycosides, palmitic acid, phytosterols, and volatile oils identified across its leaves, stems, roots, and rhizomes. Traditionally, the plant has been used for managing kidney stones, digestive disturbances, wound healing, and the relief of injuries. Moreover, modern studies have reported notable antioxidant, anti-inflammatory, antimicrobial, and anti-diabetic effects. Given its diverse biological activities, Cynodon dactylon represents a promising candidate for expanded therapeutic applications and warrants further investigation within contemporary biomedical research
Keywords: Cynodon dactylon, herbal medicine, Persian medicine, pharmacological properties, traditional application
Type of Study: Review |
Subject:
Traditional medicine
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