Volume 14, Issue 43 (Jun 2004)
J Mazandaran Univ Med Sci 2004, 14(43): 33-39 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Salehi H. A comparative study on the effect of ribaverin with and without IVIG (Intravenous imuneglobuliu) in treatment of Crimean- congo hemorrhagic Fever(CCHF) . J Mazandaran Univ Med Sci 2004; 14 (43) :33-39
URL: http://jmums.mazums.ac.ir/article-1-378-en.html
URL: http://jmums.mazums.ac.ir/article-1-378-en.html
Abstract: (12651 Views)
Background and purpose: Ïn early 2001 an epidemyic of ÇÇHF occurred in sfahan province of ÏRÂN. Âccording to some reports ÏVÏG may be useful some cases of ÇÇHF. The aim of this study was to compare the standard regimen of oral Ribavirin with or without ÏVÏG in ÇÇHF patients.
Materials and methods : 40 proven ÇÇHF patients were included in the study, %30 (12 patients) were administerad ribaverin plus ÏVÏG (case group) and %70 (28 patients) took ribaverin alone(control group). The clinical parameters of all patients were followed up for 8 weeks.
Results: The mean duration for disappearance of fever and other clinical symptoms were 4.6 and 5 days in case and control groups respectively(p= 0.27). The mean time for WBÇ and liver function tests(LFT) normalization were 3.6 and 5.8 and 3.9 and 7.5 days in case and control groups respectively)p= 0.002) and (p=0.001). there was no significant difference in mortality rate.
Çonclusion: Âlthough ÏVÏG administration declined the duration of the dizare and caused earlier improvement in clinical and para- clinical data, it seems that it did not exert any significant effect on outcome of the disease.
Materials and methods : 40 proven ÇÇHF patients were included in the study, %30 (12 patients) were administerad ribaverin plus ÏVÏG (case group) and %70 (28 patients) took ribaverin alone(control group). The clinical parameters of all patients were followed up for 8 weeks.
Results: The mean duration for disappearance of fever and other clinical symptoms were 4.6 and 5 days in case and control groups respectively(p= 0.27). The mean time for WBÇ and liver function tests(LFT) normalization were 3.6 and 5.8 and 3.9 and 7.5 days in case and control groups respectively)p= 0.002) and (p=0.001). there was no significant difference in mortality rate.
Çonclusion: Âlthough ÏVÏG administration declined the duration of the dizare and caused earlier improvement in clinical and para- clinical data, it seems that it did not exert any significant effect on outcome of the disease.
Type of Study: Research(Original) |
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Articles Copyright © The Author(s). Owned by Mazandaran University of Medical Sciences.
Contact Us
Address: Journal Office, Building No. 2, Mazandaran University of Medical Sciences, Moallem Square, Sari.Tel: +98 (011)34484874 Postal code: 48175-866 E-Mail: jmums@mazums.ac.ir Telefax: +98 (011)33262679
