Background and purpose: A post-cesarean wound complication occurs despite compliance with surgical techniques. The purpose of this study was to compare wound complications after cesarean sections in high-risk women with or without anticoagulant treatment. Materials and methods: This cross-sectional study included all women requesting elective or emergency caesarean section in Kerman Afzalipour Hospital, 2012. The subjects were selected using convenient sampling. This cross-sectional study included all women requesting elective or emergency caesarean section in Kerman Afzalipour Hospital, 2012. The subjects were selected using convenient sampling. Patients with transverse cesarean section were followed up until day 10 after delivery that they referred for removing the stitches. Patients with transverse cesarean section were followed up until day 10 after delivery that they referred for removing the stitches. Results: The mean age of participants was 28 years old. Among the subjects 71.6% underwent emergency cesarean section and post-cesarean wound was seen in 1.9%. There were 2.6% (n=18) who received anticoagulant treatment. Most of these patients aged 20 to 27 years old and the most common complications were superficial and deep wound dehiscence. There was a significant correlation between the symptoms and receiving anticoagulation (P<0.001). Significant differences were seen between the two groups in rate of wound complication following cesarean section (P <0.048). Conclusion: Use of anticoagulation in patients with cesarean section has complications such as wound dehiscence, bleeding, hematoma, and infection. Efforts should be made to increase the rate of normal deliveries, thereby reducing the number of caesarean section and its complications.